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Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from major trauma, postpartum bleeding, surgery, tooth removal, nosebleeds, and heavy menstruation. It is also used for hereditary angioedema. It is taken either orally or by injection into a vein.. Tranexamic acid is a synthetic analog of the amino acid lysine.It serves as an antifibrinolytic by reversibly.
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Before using Asam Traneksamat Capsule, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.).Some health conditions may make you more susceptible to the side-effects of the drug.
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Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. 6. It was first patented in 1957 2 and received its initial US approval in 1986. 5.
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Asam traneksamat bekerja dengan menghambat aktivitas plasmin, enzim yang bertanggung jawab dalam proses penguraian fibrin, komponen utama dari bekuan darah. Dengan menghambat fibrinolisis, asam traneksamat dapat memperlambat proses penguraian bekuan darah, memungkinkan waktu yang lebih lama bagi bekuan darah untuk membantu menghentikan perdarahan.
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nausea, vomiting, diarrhea; dizziness, feeling light-headed; mild itching or rash; or. feeling unusually happy. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Tranexamic acid side effects (more detail)
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Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding, trauma, postpartum hemorrhage, traumatic brain injury, and surgical site bleeding. Despite decades of use and a robust body of evidence, hesitancy using TXA persists.
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TRANEXAMIC ACID 500 MILLIGRAM TABLET - ORAL. (TRAN-ex-AM-ik AS-id) COMMON BRAND NAME (S): Cyklokapron. USES: This medication is used short-term in people with a certain type of bleeding disorder (hemophilia) to prevent and reduce bleeding from having a tooth pulled (extraction).
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The only FDA-approved usage for tranexamic acid (TXA) is for heavy menstrual bleeding and short-term prevention in patients with hemophilia.; this includes tooth extractions in patients with hemophilia as well as menorrhagia in these patients. Off-label uses of oral, topical, and intravenous TXA includes severely bleeding patients requiring massive transfusion protocols (MTP) or when hyper.
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Adult: 10 mg/kg as a single dose via slow inj at a rate no more than 100 mg/min immediately before tooth extraction, followed by 10 mg/kg 3-4 times daily for 2-8 days. Oral. Menorrhagia. Adult: 1,000 mg tid during menstruation as necessary for up to 4 days, may be increased for heavy bleeding. Max: 4,000 mg daily.
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Tranexamic acid has proven to be an effective treatment for heavy menstrual bleeding (HMB). It reduces menstrual blood loss (MBL) by 26%-60% and is significantly more effective than placebo, nonsteroidal anti-inflammatory drugs, oral cyclical luteal phase progestins, or oral etamsylate, while the levonorgestrel-releasing intrauterine system reduces MBL more than tranexamic acid.
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Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. breathing difficulties. changes in vision. sudden or severe pain in the chest, legs, head, or groin. unusually weak or tired.
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Untuk pemberian oral, dapat diberikan asam traneksamat 1-1,5 gram 2-3 kali sehari. Jika digunakan intravena (IV), bisa diberikan 10 mg/kg dosis Tunggal, diberikan melalui injeksi IV perlahan (tidak lebih cepat dari 1 mL/menit) segera sebelum prosedur. Dosis ini dapat dilanjutkan setelah pencabutan dengan dosis 10 mg/kg, 3-4 kali sehari.
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1 |. INTRODUCTION. Antifibrinolytic agents including tranexamic acid (TXA) have been shown to be effective at preventing bleeding complications in a variety of hemostatic challenges and reduce mortality with minimal adverse effects in some settings. 1,2 The landmark WOMAN study showed a survival benefit to the use of TXA in patients with postpartum hemorrhage. 3 In a systematic review and meta.
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Asam traneksamat menghentikan pembekuan ini sehingga mengurangi perdarahan yang tidak diinginkan. Asam traneksamat digunakan untuk mencegah atau mengurangi perdarahan untuk waktu yang singkat di banyak kondisi berbeda. Anda mungkin akan diresepkan obat ini untuk salah satu kondisi berikut. Setelah operasi prostat (pasca-prostatektomi).
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For oral dosage form (tablets): To treat heavy menstrual bleeding: Adults—Two tablets (650 milligrams per tablet) three times a day in the morning, afternoon, and evening. The tablets should not be taken more than 5 days in a row for each monthly period. Children—Use and dose must be determined by your doctor.
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Pengawasan klinis yang diperlukan bagi pasien yang mengonsumsi asam traneksamat mencakup evaluasi respons terhadap terapi, pemantauan fungsi ginjal, deteksi tanda-tanda tromboemboli, evaluasi efek samping, dan pemantauan fungsi penglihatan. [8] Penting untuk memantau respon pasien terhadap pengobatan dengan asam traneksamat terutama terkait.
