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Star 1. Summary. Sulfanilamide is a sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Generic Name. Sulfanilamide. DrugBank Accession Number. DB00259. Background. Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.


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Very bad irritation where sulfanilamide is used. Rarely, very bad effects have happened with sulfa drugs. Sometimes, these have been deadly. These effects have included liver problems, blood problems, and very bad skin reactions ( Stevens-Johnson syndrome / toxic epidermal necrolysis ).


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Sulfonamide allergies can result in various physical manifestations; however, rash is reported as the most frequently observed reaction to sulfonamide antimicrobials. Skin eruptions may occur in 1.5-3% of patients who are immunocompetent and in rates as high as 30% in patients with human immunodeficiency virus (HIV) [ 1 ].


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SULFANILAMIDE is an amino acid. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May react with azo and diazo compounds to generate toxic gases. Belongs to the Following Reactive Group(s)


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Sulfonamide (or sulphonamide) functional group chemistry (SN) forms the basis of several groups of drug. In vivo sulfonamides exhibit a range of pharmacological activities, such as anti-carbonic anhydrase and anti-t dihydropteroate synthetase allowing them to play a role in treating a diverse range of disease states such as diuresis, hypoglycemia, thyroiditis, inflammation, and glaucoma.


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Sulfonamide antibiotics have an N4 amine group in their structure which is thought to contribute to their higher incidence of allergic-type reactions. Non-antibiotic sulfonamides lack this structure. Sulfonamide antibiotics. Oral sulfonamides are rapidly excreted and very soluble in urine and are commonly used to treat infections of the urinary.


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The meaning of SULFANILAMIDE is a crystalline sulfonamide C6H8N2O2S that is the parent compound of most of the sulfa drugs.


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The prices of Sulfanilamide rose extensively in the global market during the month of November 2022, on the account of consistent incremented downstream demand, pretentious trading activities, and a shortage of inventories. In Germany, the bloc's largest economy, annual inflation slides to 11.3% from 11.6%.


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IUPAC Standard InChIKey: FDDDEECHVMSUSB-UHFFFAOYSA-N Copy CAS Registry Number: 63-74-1 Chemical structure: This structure is also available as a 2d Mol file; Other.


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Sulfanilamide, a drug used to treat streptococcal infections, had been shown to have dramatic curative effects and had been used safely for some time in tablet and powder form. In June 1937.


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Sulfanilamide is a sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antibacterial agent and a drug allergen. It is a substituted aniline, a sulfonamide antibiotic and a sulfonamide.


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Sulfanilamide is a topical vaginal antibiotic cream used to treat vulvovaginal inflammation (vulvovaginitis) caused by Candida albicans yeast (fungus) infection and susceptible bacterial infections. Common side effects of sulfanilamide include itching, burning, discomfort, redness, swelling, and skin rash. Do not use if breastfeeding. Consult your doctor if pregnant.


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The Accidental Poison That Founded the Modern FDA. Elixir Sulfanilamide was a breakthrough antibiotic—until it killed more than 100 people. An Object Lesson. In 1937, the antibiotic Elixir.


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Hypersensitivity to sulfanilamide, any sulfonamide, or any component of the formulation. Dosage and Administration Dosing: Adult. Vulvovaginitis: Intravaginal: Insert one applicatorful intravaginally once or twice daily for 30 days. Dosing: Geriatric. Refer to adult dosing. Administration. Intravaginal: Use applicator provided by manufacturer.


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Sulfonamides. Sulfonamides are a class of antibiotics that are effective against many gram-positive bacteria and gram-negative bacteria. Some sulfonamides are applied directly to the skin (topically) to treat burns and skin, vaginal, and eye infections. Sulfamethoxazole (SMX) is commonly used in combination with trimethoprim (TMP).