NDC 68645261 Simvastatin Label Information Details, Usage & Precautions
Simvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs.
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Simvastatin's usual dosage range for adults is 5 mg to 40 mg by mouth once daily in the evening. But the dosage recommendations can change if you have severe kidney problems or take certain other medications. Adolescents typically take no more than 40 mg of simvastatin once daily.
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Simvastatin dosage modifications are recommended for patients taking lomitapide, verapamil, diltiazem, dronedarone, amiodarone, amlodipine or ranolazine [ see Dosage and Administration ( 2.5) ]. Simvastatin use should be temporarily suspended in patients taking daptomycin. Lipid modifying.
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Lomitapide: May increase the serum concentration of Simvastatin. Management: Reduce the recommended simvastatin dose by 50%. Generally, limit the maximum adult simvastatin dose to 20 mg/day. A 40 mg/day dose can be considered in patients who previously received 80 mg/day for at least a year without evidence of muscle toxicity.
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The usual starting dose of simvastatin in children is 10mg. This dose may be increased to a maximum of 40mg. How to take it. Take simvastatin once a day in the evening. This is because your body makes most of its cholesterol at night, so simvastatin works better at lowering cholesterol at night than in the morning.
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60 mg single dose: simvastatin acid simvastatin: 7 16: Grapefruit Juice § (low dose) 8 oz (about 237 mL) of single-strength # 20 mg single dose: simvastatin acid simvastatin: 1.3 1.9: Verapamil SR: 240 mg QD Days 17 then 240 mg BID on Days 8-10: 80 mg on Day 10: simvastatin acid simvastatin: 2.3 2.5: 2.4 2.1: Diltiazem: 120 mg BID for 10 days.
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Low-Intensity Dosage (LDL-C Reduction <30%) Moderate-Intensity Dosage (LDL-C Reduction 30% to <50%) High-Intensity Dosage (LDL-C Reduction ≥50%) Atorvastatin: NA:. Pravastatin: 10 to 20 mg: 40 to 80 mg: NA: Rosuvastatin: NA: 5 to 10 mg: 20 to 40 mg: Simvastatin: 10 mg: 20 to 40 mg: NA: From ACC/AHA, 2018. 199 Dosages shown are total daily.
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Simvastatin (Zocor) is a statin used to lower your cholesterol to help protect your heart and blood vessels from serious, and even life-threatening, medical problems, such as heart attack or stroke.Simvastatin (Zocor) isn't meant to lower cholesterol on its own. Instead, you should take it in addition to eating a healthy diet and having a regular exercise routine.
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Simvastatin is also indicated in some genetic lipid disorders (such as heterozygous familial hypercholesterolemia) in adolescents aged 10 to 17 meeting certain criteria. The dosage of simvastatin does not need adjusting in mild-to-moderate kidney disease. Patients with severe kidney disease should be started on simvastatin 5mg daily and monitored.
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Simvastatin 80 mg dose should only be used in patients who have taken this dose chronically (e.g., for 12 months or more) without evidence of muscle toxicity If a patient on simvastatin 80 mg/day needs to initiate an interacting drug (one that will increase simvastatin concentrations); simvastatin should be switched to an alternative statin.
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Typical starting dosage: Simvastatin is often started at 10-20 mg per day. However, the dosage may range from 5 mg to 40 mg per day. You should take this drug once a day in the evening.
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The usual dosage range is 5 to 40 mg/day. Simvastatin Oral Suspension should be taken in the evening on an empty stomach [see CLINICAL PHARMACOLOGY ]. Shake bottle well for at least 20 seconds before using. In patients with CHD or at high risk of CHD, Simvastatin Oral Suspension can be started simultaneously with diet.
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For oral dosage forms (suspension or tablets): For high cholesterol: Adults—20 to 40 milligrams (mg) once a day in the evening. Your doctor may adjust your dose as needed. Children 10 years of age and older—10 to 40 mg once a day in the evening. Your doctor may increase your dose as needed.
NDC 68645261 Simvastatin Label Information Details, Usage & Precautions
Simvastatin (Zocor, FloLipid) is a prescription medication that lowers cholesterol. It works by blocking proteins the body uses to make cholesterol. Lower cholesterol levels can start to be seen within 1 to 2 months of starting the medication. Simvastatin is taken once a day in the evening, with or without food.
Simvastatin KF 20 Mg Tablet Manfaat, Dosis, Efek S...
Dosis simvastatin yang diresepkan dokter tergantung pada usia, kadar kolesterol, kondisi kesehatan, serta obat lain yang sedang digunakan oleh pasien. Secara umum, berikut adalah rincian dosis simvastatin: Tujuan: Menangani kolesterol tinggi. Dewasa: Dosis awal 10-20 mg, 1 kali sehari di malam hari. Dosis pemeliharaan 5-40 mg, 1 kali sehari.
Simvastatin Errita 10 Mg FC Tablet Manfaat, Dosis,...
Low-dose statins reduce the risk of complications like heart attack and stroke in older adults who do not have a history of heart disease but who are designated at-risk. This article will review low-dose statins, focusing on their respective uses, proven efficacy, and potential side effects.. Zocor (simvastatin) 10 mg: 20-40 mg: Not available:
