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Sequence conservation in PTEN and its interacting partners reflects... Download Scientific Diagram

The tumour suppressor PTEN regulates various cellular processes, including maintenance of genomic stability, cell survival, migration, proliferation and metabolism. Recent studies into the.


Schematic illustration of the PTEN regulated PI3KAKTmTOR signaling... Download Scientific

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Axotomyinduced PTEN deletion and anatomic regeneration following... Download Scientific Diagram

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Signaling of the phosphatase and tensin homolog deleted on chromosome... Download Scientific

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PTEN and NF1 Inactivation in Schwann Cells Produces a Severe Phenotype in the Peripheral Nervous

A nerve net is a network of dispersed epithelial sensory neurons and so-called ganglion cells 9,23,24, which are neurons that send out neurites, forming an intricate mesh of fibres on the basal.


RhoA mediates both apoptosis and failure of axon regeneration after... Download Scientific Diagram

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Phosphorylationmediated PTEN conformational closure and deactivation revealed with protein

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A visual display of the gene network connected to PTEN/TP53/CDKN1A in... Download Scientific

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Frontiers Focus on PTEN Regulation Oncology

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Schematic representation of the possible mechanisms of PTEN involvement... Download Scientific

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ceRNA network of PTEN. Figure shows the proteinprotein interaction... Download Scientific Diagram

PTEN has been recognized as a guardian of the genome since the identification of its noncanonical localization and function in the nucleus. Yet, the role of PTEN in guarding the genome relies on integration of diverse mechanisms elicited by its canonical activity in antagonizing PI3K as well as emerging noncanonical functions. In the nucleus.


Cells Free FullText Reactive Oxygen Species, Superoxide Dimutases, and PTENp53AKTMDM2

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Pten deletion causes enlarged, histoarchitecturally abnormal brains.... Download Scientific

Phosphatase and tensin homolog (PTEN) regulates apoptosis and axonal growth in the developing and adult central nervous system (CNS). Here, we show that human PTEN C-terminal PDZ interactions play.