Patent US20110021634 Processes for preparing metformin hydrochloride Google Patents
approximately 5%. To this mixture, 250 g of dicyanodiamide was added. The reactor is heated to 145°C for 3 hours. As the reaction proceeds, metformin hydrochloride precipitates from the mixture. The reactor is cooled to room temperature, demineralized water is added to the reactor and the resulting slurry is removed.
Patent US20120283332 Transdermal delivery of metformin Google Patents
April 3, 2034. Your ANDA contains paragraph IV certifications to each of the patents1 under section 505(j)(2)(A)(vii)(IV) of the FD&C Act stating that the patents are invalid, unenforceable, or will not be infringed by your manufacture, use, or sale of Empagliflozin and Metformin Hydrochloride Tablets, 5 mg/500 mg, 5 mg/1000 mg, 12.5 mg/500 mg.
Patent US7919116 Controlled release metformin formulations Google Patents
Metformin for diabetes. Take metformin just after a meal or with a snack. The most common side-effects are feeling sick (nausea), diarrhoea and tummy (abdominal) pain. These symptoms usually pass after the first few days of treatment. Keep your regular appointments with your doctor and clinics.
Patent EP1945190A1 Effervescent metformin composition and tablets and granules made therefrom
Metformin, an antidiabetic agent, was approved by the U.S. Food and Drug Administration (FDA) in 1994 for treating type 2 diabetes. This medication comes in both immediate- and extended-release formulations and is often combined with other antidiabetic agents. The off-label indications of metformin include managing gestational diabetes, addressing weight gain issues caused by antipsychotic.
Patent EP2498757A1 Reduced mass metformin formulations Google Patents
1. A tablet for oral administration comprising metformin hydrochloride, and further comprising from 0.05 to 0.5 part methylcellulose per part metformin hydrochloride by weight, wherein said tablet is free of stearate or further comprises less than 0.6% stearate by weight.
WO2004110422A1 Extendedrelease tablets of metformin Google Patents
Description. Metformin hydrochloride is an orally-administered antihyperglycemic agent, used in the management of non-insulin-dependent diabetes mellitus. Metformin hydrochloride tablets are sold in strengths of 500 mg, 850 mg and 1000 mg in the United States and elsewhere under the tradename Glucophage™.
Patent US6866866 Controlled release metformin compositions Google Patents
The invention provides compositions and methods to treat diabetes with improved formulations in which metformin is combined with at least three antioxidants that contain a stabilizing heteroatom adjacent to a saturated carbon and which help maintain a balance between antioxidant and pro-oxidant properties. The antioxidants include at least the combination of taurine, citrulline and.
Patent EP1460998A2 Extended release pharmaceutical tablet of metformin Google Patentsuche
US 6,667,054 B2. 1. METFORMIN HYDROCHLORIDE TABLETS. BACKGROUND OF THE INVENTION. Metformin hydrochloride is an orally-administered anti hyperglycemic agent, used in the management of non insulin-dependent diabetes mellitus. Metformin hydrochloride tablets are sold in strengths of 500 mg, 850 mg and 1000 mg in the United States and elsewhere.
Metformin Tablet Uses And Side Effects Is Safe For Cancer Patients?
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Patent US20110195120 Sustained Release Pharmaceutical Composition Containing Metformin
Metformin hydrochloride is the generic ingredient in twenty branded drugs marketed by Sun Pharm, Saptalis Pharms, Vistapharm, Ranbaxy, Andrx Labs Llc, Emd Serono Inc, Santarus Inc, Actavis Elizabeth, Actavis Labs Fl Inc, Ajanta Pharma Ltd, Alignscience Pharma, Alkem Labs Ltd, Amneal Pharms Ny, Amta, Apotex, Aurobindo Pharma Ltd, Barr, Beximco.
WO2004110422A1 Extendedrelease tablets of metformin Google Patents
Additional information is available in the individual branded drug profile pages. Metformin hydrochloride has fifty-six patent family members in sixteen countries. There are forty-three drug master file entries for metformin hydrochloride. Eighty-six suppliers are listed for this compound. There are four tentative approvals for this compound.
Patent WO2002036100A1 Controlled release metformin compositions Google Patents
Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is sometimes used as an off-label adjunct to lessen the risk of metabolic syndrome in people who take antipsychotics.
Patent US8581001 Metformincysteine prodrug Google Patents
feeling dizzy, light-headed, tired, or very weak; stomach pain, vomiting; or. slow or irregular heart rate. Common metformin side effects may include: low blood sugar; nausea, upset stomach; or. diarrhea. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Patent WO2007038979A1 Effervescent metformin composition and tablets and granules made
The invention provides compositions and methods to treat diabetes with improved formulations in which metformin is combined with at least three antioxidants that contain a stabilizing heteroatom adjacent to a saturated carbon and which help maintain a balance between antioxidant and pro-oxidant properties. The antioxidants include at least the combination of taurine, citrulline and.
Patent US8475841 Controlled release metformin formulations Google Patents
1. WO2021012274 - PREPARATION METHOD FOR METFORMIN HYDROCHLORIDE. The present invention provides a preparation method for metformin hydrochloride. The preparation method comprises: heating raw materials comprising dicyandiamide and dimethylamine hydrochloride by means of microwave, and making the two react at 100-160°C to obtain a product.
Patent WO2009099734A1 Pharmaceutical compositions of a combination of metformin and a
1. Process for the preparation of metformin HCl comprising the steps (a) heating a mixture of dimethylammonium chloride, dicyanodiamide, water in an amount from 0 to 20% by weight and metformin HCl in an amount from 0 to 50% by weight, each based on the total weight of dimethylammonium chloride and dicyanodiamide present in the mixture, to a temperature in the range from 70° C. to 250° C.
