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Background: Therapeutic intervention in the pathophysiology of airway mucus hypersecretion is clinically important. Several types of drugs are available with different possible modes of action. We examined the effects of guaifenesin (GGE), N-acetylcysteine (NAC) and ambroxol (Amb) on differentiated human airway epithelial cells stimulated with IL-13 to produce additional MUC5AC.


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Ambroxol Dosage. Adults: daily dose of 30 mg (one Ambroxol tablet ) to 120 mg (4 Ambroxol tablets) taken in 2 to 3 divided doses. Children up to 2 years: half a teaspoonful Ambroxol syrup twice daily. Children 2 - 5 years: half a teaspoonful Ambroxol syrup 3 times daily. Children over 5 years: One teaspoonful Ambroxol syrup 2-3 times daily.


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The efficacy of a new combination drug containing ambroxol, guaifenesin, and levosalbutamol in the treatment of productive cough in adult patients with acute bronchitis is superior to the efficacy.


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Dosis. Anak-anak (umur 6 sampai 12 tahun) Sekitar 100 sampai 200 mg, dan diminum sebanyak 4 kali per hari. *Dosis maksimal per harinya adalah 400 mg. Dewasa. Sekitar 200 sampai 400 mg, dan dikonsumsi setiap 4 jam sekali. Sedangkan untuk jenis tablet pelepasan lambat, dosis konsumsinya adalah 600 sampai 1.200 mg setiap 12 jam sekali.


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Ambroxol has an average rating of 0.0 out of 10 from a total of 1 ratings on Drugs.com. Guaifenesin has an average rating of 7.0 out of 10 from a total of 299 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 25% reported a negative effect. View all 1 reviews.


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Introduction: Ambroxol (2-amino-3,5-dibromo-N-[trans-4-hydroxycyclohexyl]benzylamine), an over-the-counter product, is a mucoactive agent and has been used widely to treat both acute and chronic respiratory diseases since 1978. This review aims to provide an overview of the clinical evidence available on the use of ambroxol in children with acute and chronic respiratory diseases.


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Guaifenesin is commonly found as part of over-the-counter combination medications for cold and cough. Read labels or ask a doctor or pharmacist before using any other cold, or cough medicine when taking guaifenesin. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines.


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Guaifenesin, a mucoactive drug, acts by loosening mucus in the airways and making coughs more productive. It is used for relief of wet cough and chest congestion due to the common cold, and remains the only legally marketed expectorant in the US (per OTC Monograph). An ingredient in numerous over-the-counter (OTC) cough/cold medications, guaifenesin has a secondary indication for use in stable.


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3. Guaifenesin. Another popular ingredient, guaifenesin, is an expectorant. Similar to ambroxol, it aids in loosening mucus and phlegm from the lungs, facilitating easier expulsion when coughing [].While both ambroxol and guaifenesin address mucus buildup, ambroxol has a slight edge due to its additional anti-inflammatory properties.


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dr. Samuel, Sp.P, FPCP. Dokter Spesialis Paru. Alo dokter, Ekspektoran fungsinya membentuk massa dahak spy mudah dikeluarkan. Mukolitik fungsinya mengencerkan massa dahak shg mudah dibatukkan. Sebenarnya mukolitik dg asetil sistein lbh baik lagi krn memutus ikatan disulfida di dahak shg dahak tdk tll lengket. Utk manfaatnya tgt kebutuhan pasien.


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Objectives: The aims of the study were to investigate the potential drug-drug interaction between salbutamol and ambroxol, the bioequivalence of the new fixed-dose combination containing salbutamol and ambroxol compared with co-administration of the two separate formulations, and to describe the safety and tolerability of the fixed-dose combination formulation in healthy Chinese volunteers.


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Kombinasi dua obat mucolitik bisa di berikan dok jika memang dari anamnesis dan pemeriksaan fisis kita menemukan lendir pada saluran napas yang sangat sulit dikeluarkan. dan untuk pemberian DMP + Guaifenesin --> kita bisa memberikan pada kondisi batuk2 alergi yang disertai dengan infeksi sekunder dok, jadi DMP sebagai antitusif batuk alerginya.


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Background Therapeutic intervention in the pathophysiology of airway mucus hypersecretion is clinically important. Several types of drugs are available with different possible modes of action. We examined the effects of guaifenesin (GGE), N-acetylcysteine (NAC) and ambroxol (Amb) on differentiated human airway epithelial cells stimulated with IL-13 to produce additional MUC5AC. Methods After.


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Aim: To evaluate the efficacy and safety of a combination drug containing ambroxol, guaifenesin, and levosalbutamol, oral solution, versus Ascoril Expectorant, syrup (combination of bromhexine, guaifenesin, and salbutamol) in the treatment of productive cough in adult patients with acute bronchitis. Materials and methods: This open-label, randomized, phase III study included patients with.


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Dosis dan Aturan Pakai Guaifenesin. Berikut adalah dosis umum penggunaan guaifenesin berdasarkan usia pasien: Dewasa: 200-400 mg, tiap 4 jam. Untuk tablet pelepasan lambat, dosisnya 600-1.200 mg, tiap 12 jam, maksimal 2.400 mg per hari. Anak usia 6-12 tahun: 100 mg, 4 kali sehari. Dosis maksimal 400 mg per hari.