Isoxsuprine Hydrochloride FDA prescribing information, side effects and uses
Fungsi & Penggunaan Untuk apa obat Isoxsuprine digunakan? Isoxsuprine adalah obat untuk penyakit pembuluh darah tertentu (misalnya, arteriosklerosis obliterans, penyakit Raynaud, penyakit Buerger, insufisiensi serebrovaskular) yang digunakan bersamaan dengan pengobatan lain. Obat ini bekerja dengan melebarkan pembuluh darah untuk membantu meningkatkan aliran darah (meningkatkan sirkulasi) ke.
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Isoxsuprine. Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator [4] in humans (under the trade name Duvadilan) and equines. Isoxsuprine is a β 2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via β 2 receptors. [5]
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Berikut adalah dosis isoxsuprine untuk pasien dewasa berdasarkan tujuan pengobatan: Tujuan: Mengatasi gangguan sirkulasi darah. Tablet: 10-20 mg, 3-4 kali sehari. Suntik: Dosis 10 mg, 3 kali sehari, diberikan melalui pembuluh darah vena (IV/intravena) atau pembuluh darah arteri (intraarterial/IA).
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Description: Mechanism of Action: Isoxsuprine, a β-agonist, increases muscle blood flow by directly relaxing the vascular smooth muscle. Pharmacokinetics: Absorption: Well absorbed from the GI tract.Time to peak plasma concentration: Approx 1 hr. Distribution: Crosses the placenta. Excretion: Excreted via urine as conjugates.Plasma elimination half-life: Approx 1.5 hr.
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Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator in humans (under the trade name Duvadilan) and equines. Isoxsuprine is a β2 adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via β2 receptors.
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Isoxsuprine is used to treat peripheral vascular diseases or the narrowing or blockage of arteries outside of the heart and brain. Examples of peripheral vascular diseases treated by Isoxsuprine are Buerger's disease and Raynaud's disease. This medicine may also be used to relieve symptoms of cerebrovascular insufficiency (blockage of one or.
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Isoxsuprine is a benzyl alcohol derivative with vasodilator activity. The mechanism of action of isoxsuprine hydrochloride is controversial, because isoxsuprine has beta-adrenergic activities that could not be offset by beta-adrenergic blockers. Although stimulation of the beta adrenergic receptor increases blood flow to produce vasodilatation, this agent may also have direct effects on the.
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Isoxsuprine. Isoxsuprine is a beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease. A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
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Isoxsuprine increases muscle blood flow, but skin blood flow is usually unaffected. Rather than increasing muscle blood flow by beta-receptor stimulation, isoxsuprine probably has a direct action on vascular smooth muscle. The generally accepted mechanism of action of isoxsuprine on the uterus is beta-adrenergic stimulation (Kaindl 1959.
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Objective: The aim of the study is to obtain insights on the short and long-term safety and effectiveness of isoxsuprine hydrochloride as a tocolytic agent in the management of PTL. Study design: In this prospective, single-center, noncomparative study, patients (with preterm labor at gestational age of 24-37 weeks) were administered intravenous (IV) infusion of 40-mg isoxsuprine hydrochloride.
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Other, less serious side effects may be more likely to occur. Continue to take isoxsuprine and talk to your doctor if you experience. chest pain or an irregular heartbeat (call your doctor if this becomes bothersome); nausea or vomiting; or. dizziness or weakness. Side effects other than those listed here may also occur.
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The invention discloses Isoxsuprines to prepare the application in preventing or treating influenza infection drug.Applicant has detected toxicity of the Isoxsuprine to cell on human squamous lung cancer system A549 and human monocyte cell line U937, antiviral activity of the Isoxsuprine in two kinds of cell line is determined in the concentration range entirely without toxicity again, as a.
