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Ambroxol is a medication indicated for airway secretion clearance therapy. Generic Name. Ambroxol. DrugBank Accession Number. DB06742. Background. Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin.


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What is ambroxol? Early in 2023, researchers will launch a phase 3 clinical trial of ambroxol, a cough medicine that is available over the counter in many countries, to study its ability to slow.


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Background: Belonging to the group of expectorants, ambroxol is an active substance with a long history that influences parameters considered to be the basis for the physiological production and the transport of the bronchial mucus. Therefore, ambroxol's indication is 'secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired.


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Ambroxol has been first marketed in 1979, and is currently available in many countries. Ambroxol lozenges for the treatment of sore throat are available since 2002. For the treatment of mild diseases of the respiratory tract single doses of 20 to 75 mg are used. In addition to these indications ambroxol is used in the treatment of infant.


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Mechanism of Action: Ambroxol is a mucolytic agent that increases respiratory tract secretion by enhancing the production of pulmonary surfactants and stimulating ciliary activity. This results in the improvement of mucociliary clearance and enhancement of fluid secretion which facilitates expectoration and eases cough.


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Etabroxol Tablet. Etabroxol is a metabolite of Bromhexine. It possesses mucokinetic (improvement in mucus transport) and secretolytic (liquefies secretions) properties. Etabroxol stimulates the serous cells of the glands of the mucous membrane of bronchi, increasing the content of mucus secretion. The mucolytic effect is associated with.


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Further information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Lists the various brand names available for medicines containing ambroxol. Find information on ambroxol use, treatment, drug class and molecular formula.


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Background. Ambroxol is a mucolytic compound and the main ingredient of over-the-counter cough medicines sold in many countries. Syrup, tablet, and other forms are used at doses of 30 to 120 mg per day to reduce or thin mucous secretions and ease sore throat pain. The most common side effects are gastrointestinal.


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Expert advice for Ambroxol. Ambroxol helps in thinning and removal of the mucus (slimy and sticky substance) from the airways, thereby treats various respiratory conditions. Measure the syrup with a special dose-measuring spoon or cup, not a regular table spoon. Do not use Ambroxol for more than 14 days, without your doctor's advice.


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Ambroxol is a potential disease-modifying small molecule that targets α-synuclein aggregation (Table 1). Since 1979, ambroxol has been using as a drug for cough . A report indicates ambroxol blocks autophagy and driving cargo towards the secretory pathway .


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Ambroxol is a commercially available inhibitor of Na v 1.8, a crucial player in the pathophysiology of neuropathic pain, and Na v 1.7, a particularly exciting target for the treatment of chronic pain. In this review, we discuss the analgesic mechanisms of action of ambroxol, as well as proposed synergistic properties, followed by the.


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Ambroxol, bromhexine, carbocysteine, erdosteine, NAC, and sobrerol have all been awarded well-established status by regulatory authorities and are available as OTC or prescription products for selected indications. This work aims to evaluate the evidence-based efficacy and safety of these substances in the therapy of upper respiratory airways.


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Etabroxol merupakan obat yang termasuk ke dalam golongan obat keras sehingga pada setiap pembeliannya harus menggunakan resep dokter. Selain itu, dosis penggunaan etabroxol juga harus dikonsultasikan dengan dokter dan apoteker terlebih dahulu sebelum digunakan, karena dosis penggunaannya berbeda-beda setiap individu tergantung berat tidaknya.


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Soup, broth, tea, or another hot beverage. Warm liquids like soup and tea help add moisture while providing immediate relief for sore and scratchy throats. Warm liquids also help keep you hydrated.


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Ambroxol administration was initiated with a starting dose of 5 mg/kg/d divided into 3 equal doses. It was suggested to increase the doses gradually according to clinical outcomes of ambroxol at follow-up visits, no more than the maximal dose (25 mg/kg). Patients received an escalating dose of oral ambroxol (mean [SD] dose, 12.7 [3.9] mg/kg/d.


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Ambroxol is also used as a pain reliever for sore throats as it has a local numbing effect. Ambroxol starts working about 30 minutes after it has been taken. The breakdown of acid mucopolysaccharide fibers makes the sputum thinner and less viscous and therefore more easily removed by coughing. Although sputum volume eventually decreases, its.