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Diazepam rektal bisa diberikan dalam dosis sebagai berikut: Berat badan >10 kg: dosis 0,5 mg/kg, dapat diulang bila perlu, maksimal 10 mg. Usia 2−5 tahun: dosis inisial 0,5 mg/kg, dibulatkan ke atas sesuai dosis yang tersedia. Usia 6−11 tahun: dosis inisial 0,3 mg/kg, dibulatkan ke atas sesuai dosis yang tersedia.
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In contrast, only α1 (V279A) enhances the efficiency of DZ-to-pore linkage, whereas mutations in the other two subunits have no effect. These observations show that the central residue in the M2-M3 linkers of distinct subunits in synaptic α1β2γ2 GABA A Rs contribute asymmetrically to the intrinsic closed-open equilibrium and its modulation.
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Diazepam is mainly metabolised in the liver by CYP2C19 and CYP3A4 to its major active metabolite, desmethyldiazepam, and two minor active metabolites, temazepam and oxazepam. According to a study, approx 3% of Caucasians and 15-20% of Asians are poor metabolisers of CYP2C19 or have decreased or absent CYP2C19 enzyme activity. Available.
Diazepam Wikipedia
Diazepam is a medication that belongs to the class of benzodiazepines, which are used to treat anxiety, seizures, muscle spasms, and other conditions. Learn how to use diazepam safely and.
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Apo-Diazepam: Diazepam belongs to the class of medications called benzodiazepines. It is used for the short-term relief of symptoms of mild-to-moderate anxiety or alcohol withdrawal (such as agitation). It is also used for reducing muscle spasms. It works by slowing down the nerves in the brain (i.e., central nervous system).
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Diazepam is used to relieve symptoms of anxiety and alcohol withdrawal. This medicine may also be used to treat certain seizure disorders and help relax muscles or relieve muscle spasm. Diazepam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow.
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Common side effects of flumazenil may include: headache, dizziness; nausea, vomiting; increased sweating; flushing (sudden warmth, redness, or tingly feeling); vision problems; or. pain where the medicine was injected. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
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Absorption. After oral administration, it is considered that diazepam is rapidly and completely absorbed from the gastrointestinal tract as >90% of diazepam is absorbed and the average time to achieve peak plasma concentrations is 1 - 1.5 hours with a range of 0.25 to 2.5 hours 15,16,6.. Absorption is delayed and decreased when administered with a moderate fat meal 15.
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confusion, paranoia; or. new or worsening seizures. Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury. Common diazepam side effects may include: drowsiness; feeling tired; muscle weakness; or. problems with balance or muscle movement.
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Anxiety. Indicated for management of anxiety disorders or for short-term relief of the symptoms of anxiety. 2-10 mg PO q6-12hr, OR. 2-5 mg IV/IM q3-4hr if necessary, for moderate anxiety disorders; 5-10 mg IV/IM q3-4hr for severe anxiety disorders.
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Kandungan: Diazepam; Kemasan: Dus, 10 Ampul @ 2 ml; Produksi: Sanbe Farma; Harga Valisanbe Injeksi: Rp. 16.000 - Rp. 22.000/ampul; Kegunaan Valisanbe. Obat valisanbe digunakan untuk premedikasi atau pemeliharaan dan pemulihan anestesi serta untuk memberikan efek tenang dalam prosedur bedah dan medis minor.
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Berikut ini adalah dosis diazepam bentuk enema sesuai tujuan penggunaannya: Tujuan: Membantu meredakan kejang. Dewasa: 0,5 mg/kgBB, dosis dapat diulang tiap 12 jam. Dosis maksimal 30 mg. Anak-anak: Untuk anak usia 2-5 tahun, dosisnya 0,5 mg/kgBB, sedangkan untuk anak usia 6-11 tahun, dosisnya 0,3 mg/kgBB.
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Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures. It can be taken orally (by mouth), as a.
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BRAND NAME(S): Valium. Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage. USES: Diazepam is used to treat anxiety and muscle spasms.The injection form is used when the medication cannot be taken by mouth. It is also used in patients with alcohol withdrawal to prevent seizures and treat other symptoms (e.g., agitation.
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Hepatic; diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam.. Rectal: Undiluted 5 mg/mL parenteral formulation (filter if using ampul): Infants, Children, and Adolescents: 0.5 mg/kg/dose then 0.25 mg/kg/dose in 10 minutes if needed.
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Diazepam is a controlled substance drug used to treat anxiety, alcohol withdrawal, muscle spasms, and certain types of seizure. Learn more here.
